Anti-RANKL (Polyclonal), ALEXA Fluor 594

8600

None

RANKL

O14788

IF(IHC-P)

590nm/617nm

1ug per 1ul

Extracellular

ALEXA FLUOR® 594

Alexa conjugate 1

IF(IHC-P)(1:50-200)

Polyclonal Antibody

Polyclonal Antibodies

Anti-RANKL Polyclonal

Purified by Protein A.

RANKL Polyclonal Antibody

Polyclonals and antibodies

Conjugated Primary Antibody

Alexa Fluor,ALEXA FLUOR® 594

Rabbit (Oryctolagus cuniculus)

For facs or microscopy Alexa 1 conjugate.

This antibody reacts specifically with RANKL

No modification has been applied to this antibody

KLH conjugated synthetic peptide derived from human RANKL

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2; Tumor necrosis factor ligand superfamily member 11; Osteoclast differentiation factor; Osteoprotegerin ligand; Receptor activator of nuclear factor kappa-B ligand; TNF-related activation-induced cytokine; TNFSF11

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.