Important information

Name

Rabbit Anti Human TNFRSF11A Antibody-Non-conjugated

Size

100ug

Catalog number

CSB-PA08467A0Rb_100ug

Price

302 €

Extended information

Antibody isotype

IgG

Purity

>95%

Species reactivity

Human

Immunogen species

Human

UniProt ID

Q9Y6Q6

French translation

anticorps

Alias

TNFRSF11A

Conjugation

Non-conjugated

Purification method

Protein G purified

Clonality

Polyclonal antibody

Latin name

Oryctolagus cuniculus

Antibody category

Polyclonal Antibodies

Synonym name

TNFRSF11A Human Antibody

Format

Liquid, diluted in buffer

Tested applications & recommended dilutions

ELISA,WB;Recommended dilution:WB:1:1000-1:5000

Long name

Rabbit Antibody against Human TNFRSF11A, Non-conjugated

Short name of the antigen

Tumor necrosis factor receptor superfamily member 11A protein

Buffer composition

Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Immunogen type

Recombinant human Tumor necrosis factor receptor superfamily member 11A protein (28-202AA)

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.

Shipping and storage

TNFRSF11A Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.

About

Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

Properties

If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Background

RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate na?ve T cell proliferation and to promote the survival of RANK + T cells. RANK is also expressed in a variety of tissues including skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. The RANK/RANKL interaction is important in the regulation of osteoclastogenesis and in dendritic-cell-mediated T cell immune responses. Impairments in RANK signaling have been implicated in the induction of expansile osteolysis and Paget disease of bone (PDB2). Recombinant human sRANK receptor is a 19.3 kDa polypeptide containing the TNFR homologous cysteine rich portion of the extracellular domain of RANK receptor (175 amino acid residues).