Important information

Name

RANK, Ectodomain (Receptor Activator of NFkB) Antibody

Size

50ug

Catalog number

MBS611176

Price

608 €

Extended information

Other names

N/A

Gene name

N/A

Gene name synonims

N/A

Other gene names

N/A

Concentration

N/A

Immunoglobulin isotype

N/A

Species reactivity

Human

Purification method

Purified

French translation

anticorps

Category

Antibodies

Clonality

Polyclonal

Alternative name4

RANK, Ectodomain

Clone

Polyclonal antibody

Host organism

Host: Rabbit; Source: Human

Tested for:

Western Blot (WB), Flow Cytometry (FC/FACS)

Form/Appearance

Supplied as a liquid. No preservatives added.

Alternative name3

RANK, Ectodomain (Receptor Activator of NFkB)

Alternative name2

RANK, Ectodomain (Receptor Activator of NFkB)

Alternative name1

Anti-RANK, Ectodomain (Receptor Activator of NFkB)

Alternative name5

Anti -RANK, Ectodomain (Receptor Activator of NFkB)

Specificity and cross-reactivity

Recognizes human RANK. Detects a band of ~24kD by Western Blot.

Properties

If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Advisory

In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Storage and shipping

Store at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Description

productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.

Additional description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Gene

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory