Important information

Name

RANK Receptor protein

Size

100 µg

Catalog number

30R-AR001

Price

327 €

Extended information

Reactivity

Human

Shipping conditions

Blue Ice

Category

Proteins

Type of protein

Recombinant

Expression System

Escherichia coli

Grade & Purity

Grater than 98% pure

Antibody Subtype

Recombinant Proteins

Area of research

Cytokines & Growth Factors

Tested for

Please refer to the datasheet

Bioactivity

Determined by its ability to suppress the production of IFN-gamma from human PBMCs.

Form & Buffer

Lyophilized from 10 mM Na3PO4, pH 7.2. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.

Storage

Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Residues

Region of RANK receptor protein corresponding to amino acids MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.