RANK Antibody

RANK

8792

human

rabbit

Q9Y6Q6

WB,IHC-P

TNFRSF11A

anticorps

freeze-dried

Polyclonal antibody

Polyclonal antibody

IgG polyclonal antibody

Immunogen affinity purified.

Tumor necrosis factor receptor superfamily member 11A

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml

If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Tumor necrosis factor receptor superfamily member 11A | Osteoclast differentiation factor receptor | ODFR | Receptor activator of NF-KB | CD265 | Tnfrsf11a | Rank | Q9Y6Q6

A synthetic peptide corresponding to a sequence in the middle region of human RANK (235-262aa YRKKGKALTANLWHWINEACGRLSGDKE), different from the related mouse sequence by seven amino acids.

The RANK Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.

Keep the RANK Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.

Receptor Activator of Nuclear Factor κ B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. It is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, this gene is mapped to 18q22.1.

1. Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ (1999). "Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families". Endocr. Rev. 20 (3): 345–57. 2. Theill LE, Boyle WJ, Penninger JM (2002). "RANK-L and RANK: T cells, bone loss, and mammalian evolution". Annu. Rev. Immunol. 20: 795–823. 3. Wong BR, Josien R, Choi Y (1999). "TRANCE is a TNF family member that regulates dendritic cell and osteoclast function". J. Leukoc. Biol. 65 (6): 715–24.